Lack of sleep zaps cell growth, brain activity.

Lack of adequate sleep can do more than just make you tired. It can short-circuit your system and interfere with a fundamental cellular process that drives physical growth, physiological adaptation and even brain activity, according to a new study from the University of Tennessee, Knoxville. Albrecht von Arnim, a molecular biologist based in the Department of Biochemistry and Cellular and Molecular Biology, studied plants but said the concepts may well translate to humans. His team examined h...
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Fovista® Treatment for wet Age-Related Macular Degeneration (AMD).

Fovista is a promising new treatment for wet AMD is currently in Phase 3 clinical trials. It is designed to target platelet derived growth factor (PDGF) in combination with anti-VEGF drugs to disrupt the formation of abnormal new blood vessels in wet AMD. Patients with wet AMD are helped by drugs that block the growth and leakage of abnormal blood vessels. Currently, the most frequently used drugs that are injected into the eye are Eylea®, Lucentis®, or Avastin®. On average, patients who rece...
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Killing HIV by targeting its sweet tooth

Scientists have discovered that HIV has a voracious sweet tooth, which may be its Achilles’ heel, reports a new study from Northwestern Medicine and collaborators. After the virus invades an activated immune cell, it craves sugar and nutrients from the cell to replicate and fuel its wild growth throughout the body. Teams from Northwestern University and Vanderbilt University have reportedly discovered a way to block the virus from feasting on the glucose in an infected patient’s bloodstream. ...
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