Supercoiled DNA is far more dynamic than the “Watson-Crick” double helix

Researchers have imaged in unprecedented detail the three-dimensional structure of supercoiled DNA, revealing that its shape is much more dynamic than the well-known double helix. As reported online today in the journal Nature Communications, the simulations also show the dynamic nature of DNA, which constantly wiggles and morphs into different shapes, a far cry from the commonly held idea of a rigid and static double helix. Improving our understanding of what DNA looks like when it is in the...
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