Scientists grow functional vocal cord tissue in lab.

UW-Madison scientists have grown human vocal cord tissue in a dish, which made sound when transplanted into voice boxes from cadaver dogs, a development that could lead to better treatments for people with voice disorders. Such implants likely won’t be ready for human testing for years. But re-creating the tissue, known as a vocal fold, and showing it was functional in dog larynges and was not rejected by a mouse model of the human immune system are significant steps, the researchers said. “We n...
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Drug prevents Type 1 diabetes in mice

A compound that blocks the synthesis of hyaluronan, a substance generally found in in all body tissue, protects mice from getting Type 1 diabetes.Nadine Nagy and Paul Bollyky and their colleagues found that a drug helped prevent the onset of Type 1 diabetes in mice. They hope to find out if the drug will work similarly in humans. Type 1 diabetes, formerly called juvenile diabetes, afflicts one in 300 people in the United States. A compound that blocks the synthesis of hyaluronan, a substance ...
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Scientists Can Now 3D-Print The Building Blocks of Life

Scientists have developed a 3D-printing method capable of producing highly uniform blocks of embryonic stem cells. These cells are capable of generating all cell types in the body and could be used as the ‘Lego bricks’ to build tissue constructs, larger structures of tissues, and potentially even micro-organs. They could also be used for stem cell regulation and expansion, regenerative medicine, drug screening studies, and potentially even for the construction of micro-organs. “It was really ...
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Scientists discover how to trap cancer cells before they spread.

Researchers at the Francis Crick Institute and the University of Copenhagen have discovered a new way to 'fence in' a tumor and help stop cancer cells from spreading. Tumors cause cells called fibroblasts to stiffen the surrounding tissue so that cancer cells can grip it, allowing them to tunnel through to the blood stream and spread around the body. They showed that adding experimental drugs, reprogrammed fibroblasts helped in stopping them from 'stiffening' the tissue around tumors. This he...
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GM pig organs could soon be transplanted into humans

Pig organs could soon be transplanted into patients after Harvard University scientists discovered a way to genetically modify pig DNA so it is more compatible with humans. Scientists have spent decades trying to engineer pig tissue so that it would not be rejected by the human body, but the immune system has always prevented success. A major hurdle in transplanting pig organs into humans has been overcome by the scientists. All pig DNA carries the porcine endogenous retrovirus which infects ...
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