Bioprinters are 3D printer for biology that are capable of creating living Human Tissues on Demand

BioBots builds software, hardware, and wetware to design and engineer living things.

Allevi is the 3D printer for biology that is trusted by leading researchers around the world. Learn more about how Allevi can be used in your lab today.

microfluidic technology powers RX Bioprinters and provides unprecedented flexibility and control over 3D heterogeneous tissue fabrication.

Lab-on-a-Printer™ technology was developed specifically to enable the biofabrication of highly complex, heterogeneous 3D tissue. This technology is embodied through a growing portfolio of disposable and modular microfluidic printhead cartridges, each offering sophisticated tissue design features. Utilizing the concept of coaxial flow focusing, a cell-laden biological fiber is generated within the printhead cartridge and patterned into a 3D structure. This unique 3D printing mechanism opens entirely new doors in the design of 3D printed tissue by allowing multiple different cell types to be precisely located or combined seamlessly during printing. Lab-on- a-Printer™ technology is compatible with a range of low and medium viscosity BioInks that are particularly well suited to promoting tissue function due to a combination of favorable mechanical properties and high ratios of bioactive and cellular content to scaffold components. Importantly, Lab-on- a-Printer™ technology is a forward looking platform that is able to harness rapidly growing advancements in microfluidics to reach the incredible levels of sophistication necessary to truly recapitulate the complexity of native organ tissue.

Microfluidics is the science of manipulating and controlling fluids, usually in the range of microliters (10-6) to picoliters (10-12), in networks of channels with dimensions from tens to hundreds of micrometers. This discipline takes its origins in the early 1990’s and has grown exponentially. It is viewed as an essential tool for life science research or in a larger way in biotechnologies.

It is a very attractive technology for both academic researchers and industrial groups since it considerably:

Microfluidics deals with very precise fluid control, under small volumes and space, micro meaning one of the following features:

Figure 1: Example of a microfluidic chip with channels thinner than 1 mm
Figure 1: Example of a microfluidic chip with channels thinner than 1 mm

Small volumes (µL, nL, pL, fL)
Small size (mm, µm)
Low energy consumption

Active microfluidics refers to fluid handling made by active components as microfluidic pumps or microfluidic valves. Microfluidic pumps supply fluids in a continuous way or are used for dosing whereas the microfluidic valves can inject precise volumes of sample or buffer.

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