Chinese Academy of Science’s Institute of Zoology, used the enzyme ADH1B, which accelerates the breakdown of alcohol in the body.
Alcohol dehydrogenase 1B is an enzyme that in humans is encoded by the ADH1B gene.
The protein encoded by this gene is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol (beverage alcohol), retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. The encoded protein, known as ADH1B or beta-ADH, can form homodimers and heterodimers with ADH1A and ADH1C subunits, exhibits high activity for ethanol oxidation and plays a major role in ethanol catabolism (oxidizing ethanol into acetaldehyde). The acetaldehyde is further metabolized to acetate by aldehyde dehydrogenase genes. Three genes encoding the closely related alpha, beta and gamma subunits are tandemly organized in a genomic segment as a gene cluster
Chinese scientists have genetically engineered a probiotic that speeds up the breakdown of alcohol and protects the liver from booze-related damages.
Just 20 minutes after alcohol exposure, the group of untreated mice displayed signs of drunkenness, such as failing to get back on their feet after being placed on their backs.
On the other hand, half of the mice that received the probiotic managed to turn themselves over after an hour.
Meanwhile, a quarter of those that were treated did not have a problem getting back on their feet at all.
Alcohol dehydrogenase 1B is an enzyme that in humans is encoded by the ADH1B gene.
Additional tests showed that blood alcohol levels in the untreated group continued to rise, while those in the treated group began to fall.
The lower levels of alcohol suggested lower chances of liver & intestine damage, as well as a cure to liver diseases, when expanded.
Taking a probiotic pill before a night out could prevent a hangover and stave off alcohol’s lasting ill effects, academics say.