Nanoparticles known as Cornell dots, or C dots, have shown great promise as a therapeutic tool in the detection and treatment of cancer. Now, the ultrasmall particles – developed more than a dozen years ago by Ulrich Wiesner, the Spencer T. Olin Professor of Engineering – have shown they can do something even better: kill cancer cells without attaching a cytotoxic drug. A study led by Michelle Bradbury, director of intraoperative imaging at Memorial Sloan Kettering Cancer Center and associ...

Researchers have discovered that a protein found naturally in cells that provides some protection from viruses is responsible for creating mutations that drive resistance to tamoxifen treatment in breast cancer. Because the protein, known as APOBEC3B, is found in elevated quantities in other kinds of cancer cells, the finding explains differential responses to treatment and opens the door to boosting the effectiveness of tamoxifen and related breast cancer therapies that inhibit the ability of e...

Far too many diseases do not have a proven means of prevention or effective treatments. We must gain better insights into the biological, environmental, and behavioral influences on these diseases to make a difference for the millions of Americans who suffer from them. Precision medicine is an emerging approach for disease treatment and prevention that takes into account individual variability in genes, environment, and lifestyle for each person. While some advances in precision medicine have be...

Photoswitches are a family of small-molecules designed to photo-modulate the activity of specific signaling proteins: One color turns the protein ‘on’; a different color turns it ‘off’. Photoswitches were conceived at the Nanomedicine Development Center for the Optical Control of Biological Function at UC Berkeley Light-sensitive proteins are changing the way scientists study how new drug candidates affect critical properties of heart and nerve cells. The proteins, discovered by Max Planck re...

Poze is the most user-friendly and affordable way to improve your posture. They have cut the noise and focused on a real problem: how to avoid bad habits. Poze is a wearable device that has no app, no charging, and no diagrams. The certified technology calculates the angle of your back’s posture. If you slouch for 1 minute, Poze silently buzzes reminding you to straighten back up. In 3 weeks your muscles will feel normal when sitting or standing tall. Attach Poze with a self-adhesive hypo-all...

Original Xiaomi Mi Plant Flowers Tester is a perfect tool to test the soil conditions (moisture / light / pH / humidity / temperature) of fruits, flowers, vegetables, shrubs, etc.. Ideal and necessary monitor for gardeners, vegetable and fruit growers, and all those who plant trees and grass. When connected with Xiaomi Smart Home, you can control the plants conditions on your phone. With high accuracy and easy operation. You can take good care of your plants. Flowers and Plants Monitor is...

When was the last time you experienced inconvenient train delays? Do you wish that railway companies could do a better job of predicting when breakdowns will occur? Whereas in the past, maintenance traditionally consisted of checking rail vehicles at designated operating centers on a regular basis to resolve obvious problems and maintain machines, digital technologies are opening the door to a new level of service. Siemens' Allach locomotive plant on the outskirts of Munich is a high-tech ...

What happens inside your body when you start a fitness routine? How does a change in your diet affect your biochemistry? What can you do to get the best out of your body? In order to provide answers to these questions,Metabolomic Discoveries GmbH has developed Kenkodo, a personalized metabolomics testing service to help you know your body better. Kenkodo connects a person’s lifestyle to the biochemical state of the body. Metabolomics is at the cutting edge of biotechnology. For the first time...

Nanoscale secondary ion mass spectrometry (nanoSIMS or nano secondary ion mass spectrometry) is a nanoscopic scale resolution chemical imaging mass spectrometer based on secondary ion mass spectrometry. It works based on a coaxial optical design of the ion gun and the secondary ion extraction, and on an original magnetic sector mass spectrometer with multicollection. NanoSIMS not only refers to the technique used, but also the mass spectrometer specialized for this method. There are currently...

Natural light has all kinds of health benefits: improving sleep, mood, metabolism, and even workplace performance. But every room has its dark spaces, and sometimes you can’t avoid turning the lights on when it’s sunny out—wasteful as it seems. Sit the globe-like smart mirror in a sunny spot, orient its “pointer” toward where you want more light, and it will do the rest. The solar-powered Lucy, equipped with photo sensors and photovoltaic cells, will tilt its mirror to follow the sun, ensurin...

The way we drink our tea and coffee has changed. The many distractions of modern life mean we often leave our hot drink to become lukewarm, or worse, cold. So all that time and effort in preparing it goes down the drain. It was clear that the household mug needed to be brought up to date. For tea or coffee to taste its best, it has to be hot - ideally 60°C (140°F) to 65°C (150°F). When you make a hot drink in a standard mug, it will only remain in the perfect temperature range for a couple of...

TiBe Connect is a Smart Keyfob Two-in-One ! 1 . A tracking device to never lose your stuff again. 2. A smart button to make your daily life easier. Send a text message with your GPS location to a friend Order your favorite Pizza Find your Car : stick TiBe on your dashboard, the App’ will remember where your parked it ! Switch off the lights from someplace else, if you forgotten to do it ! https://youtu.be/BU3VB_IjdbE   You can customize each TiBe according to the things...

Researchers have shown that when parts of a genome known as enhancers are missing, the heart works abnormally, a finding that bolsters the importance of DNA segments once considered “junk” because they do not code for specific proteins. On the left, a mouse embryo showing enhancer activity (blue staining) in the developing heart. On the right, a closeup of this heart, showing that the enhancer is active in the left ventricle, left atrium, and right atrium of the heart. (Credit: Mammalian Func...

A high-glycemic load diet is linked to higher depression symptoms, fatigue and mood disturbance compared to a low-glycemic load diet, a new study finds. The glycemic load (GL) helps people assess how food portions affect blood sugar levels, and can be useful for people with diabetes who may be unsure about how a meal could affect their management. Foods with a high GL are those with a high carbohydrate value that influence blood glucose levels quickly. Bread, rice and many breakfast cereal...

At some point in their lives, 15 percent of people with diabetes will develop a painful and hard-to-treat foot ulcer. Twenty-four percent of those affected will require a lower-leg amputation because of it. And, in some instances, what seems like a harmless sore might even lead to death. A Northwestern Engineering team has developed a new treatment for this severe and potentially deadly complication of diabetes. Called a “regenerative bandage,” the novel material heals diabetic wounds four ti...

A Chinese government-backed company intends to fly up to 20 passengers to the edge of space, more than any other commercial space travel firm is currently planning. The China Academy of Launch Vehicle Technology has designed a winged rocket that takes off under its own power (it doesn’t need to be carried to a high altitude by another aircraft, as is the case with many of the other proposed space tourism projects). “The vehicle will take off vertically like a rocket and land on the runway aut...

Hand Dryer is something you always see in public restrooms, but never in a home. HÖMDRY is the first Hand Dryer specifically built and designed for your home's bathroom or kitchen. HÖMDRY is compact, affordable, hygienic, cordless and environmentally friendly. HÖMDRY can be placed on it's base or mounted on the wall. Eliminate paper towels and dirty rags and support HÖMDRY! 99.9% of the population uses either, some sort of reusable towel, paper towel or nothing at all to dry their hands ...

Breathometer Mint is a compact wireless device that works with your smartphone to help you understand and improve your oral health. Through a highly sophisticated array of sensors, Mint can detect the signs that harmful bacteria leave behind and accurately report through the Mint app. In a matter of seconds, Mint will draw, analyze, and record the state of your oral and breath health utilizing our smartphone app. Preloaded with effective times to measure yourself, carry Mint with you for ...

With hundreds of thousands of refugee children entering the German school system, teachers face unprecedented challenges. Teaching a child a second language individually is something that most classrooms cannot do. However, language acquisition is imperative to integration. Could technical assistants be used to help prepare immigrant children for school and teach them a new language? L2TOR, pronounced 'el tutor' which stands for 'Second Language Tutoring Using Social Robots,' is a new project...

The UN estimates that the global population is increasing by about 80 million people each year. By the year 2050, nine billion people will need to be fed. The middle class will continue to grow, and with greater prosperity and urbanization, food habits will change: Meat, fish, dairy products, and eggs will become staples on many menus. How will all these people be adequately fed, and how will the increasing demand for meat be satisfied in the future? Amino acids from Evonik Industries, used a...

In emergency situations such as terrorist attacks, natural catastrophes, and fires, there is always a risk of mass panic leading to deadly crowd disasters. But what causes mass panic and where are the danger zones? Researchers from the Max Planck Institute for Human Development, Disney Research Zurich, ETH Zurich, and Rutgers University have examined these questions in a virtual environment. Their results have been published in the Journal of the Royal Society Interface. The reserac...

WOOLF is a legal and simple device that you put at your wrist to be warned of speed traps, school zones, & red light cameras... You no longer have to worry about checking speed limits and other sensitive points, Woolf will do this for you. Woolf is made of high quality leather that is water resistant and specially designed for bike clothing. It is functional, thin and comfortable to wear even with tight gloves The dedicated app uses the leading world mapping speed limit service and oth...

LVL is a hydration monitor from BSX, You might know that name from the company’s first product, the Insight lactate threshold monitor. Why Monitor Hydration? Think of LVL as the evolution of that technology, says BSX co-founder Dustin Freckleton, MD. “Lactate threshold was always a mid-range goal on the way to what we truly wanted to do, which was measure hydration,” he says. Freckleton’s interest is partly personal: in the midst of studying for med school exams, he suffered a stroke partly ...

Gravity Sketch is shaking up the world of 3D creation. It is based on sketching, the most natural way to land your ideas. For years 3D design tools have been difficult to learn and a nightmare to use. We have designed a user experience that makes sense for everyone. We have lowered the barriers to 3D literacy, striving to make digital 3D creation easier for designers, artists, and makers alike. Our first product, Gravity Sketch iOS is already being used by thousands of creators all over th...

The Saver Emergency Breath System is a personal life saving device that allows you to breathe clean air in the event of a fire. Saver helps prevent smoke inhalation which is the leading cause of fire fatalities. Saver filters chemical substances and removes carbon monoxide and toxic gases giving you up to 5 minutes of breathable air—Enough to get you and your family safely out of the house during a fire. https://youtu.be/XAaZjtjcHZA Triple Filter Technology Saver is designed with a tripl...

Scientists in Germany have achieved internet speeds averaging a sustained 1 terabit per second (1 Tbps) on an optical fibre network. At that speed, you're getting a data transmission rate that's a whopping 1,000 times faster than services like Google Fibre, which delivers 1 gigabit per second (1 Gbps). While Google Fibre's 1 Gbps itself might be considered sufficiently drool-worthy for those of us constrained to the even slower speeds of ADSL and cable, it can't hope to compete to the almo...

Northwestern Medicine scientists, working with the Pediatric Emergency Care Applied Research Network (PECARN), recently assessed whether an RNA biosignature of the body’s response to infection could distinguish if infants 60 days or younger with fever were experiencing a serious bacterial infection. The results, published in the Journal of the American Medical Association, show how RNA biosignatures may be an alternative – and more accurate – method to identify infants with bacterial infectio...

Phototactic behaviour directs some bacteria towards light and others into darkness: This enables them to utilize solar energy as efficiently as possible for their metabolism, or, otherwise, protects them from excessive light intensity. A team of researchers headed by Clemens Bechinger from the Max Planck Institute for Intelligent Systems and the University of Stuttgart, as well as colleagues from the University of Düsseldorf have now found a surprisingly simple way to direct synthetic microswimm...

A team of 13 students from the University of Virginia in Charlottesville, VA, has earned First Place in NASA’s 2015-2016 University Aeronautics Design Challenge for their concept of an electric-powered, commuter-sized airplane featuring “green aviation” technologies. Sponsored by NASA’s Aeronautics Research Mission Directorate, the engineering design contest specifically asked students to incorporate distributed electric propulsion, or DEP, in their concept for an airplane that could enter se...

1.6 billion people worldwide have no access to electricity. Blue Freedom - the smallest and lightest hydropower plant in the world - enables people without access to a power grid the freedom to produce energy themselves. Complete with ultramarine rotor blades, the microturbine can be used by anyone with access to flowing water to produce and store electrical energy in an eco-friendly way that preserves biodiversity. Blue Freedom is world's smallest hydropower plant. It can be used by anyone wit...