The Sydney start-up DetectED-X has directed its breast cancer diagnosis tool at the coronavirus, drawing on pandemic cases globally with support from healthcare and industry leaders to ramp up COVID-19 detection.
The only online image-based COVID-19 diagnosis improvement tool for healthcare workers is launched by University of Sydney spinoff DetectED-X, drawing on its global experience and outcomes in breast cancer detection and patient cases from the coronavirus pandemic.
DetectED-X provides a web-based system that allows clinicians located anywhere to diagnose de-identified radiologic images where each image interaction is being instantly recorded. Specifically, some cases will demonstrate disease appearances, some will not.
The cloud-based technology, developed by Australian-based radiation and imaging experts DetectED-X, will help doctors and radiologists diagnose cases faster and more accurately. Computed tomography (CT) lung scans, which produce cross-sectional images using X-rays and computers, have typically been used after swabs are taken, to identify the extent and location of the disease; the CT scans produce images within minutes and are also able to diagnose COVID-19 in the very early stages that escape detection with the nucleic acid tests. As COVID-19 testing ramps up, the platform could facilitate rapid training where required – with modules able to be completed in as little as an hour – upskilling staff unfamiliar with lung radiology to prepare standardised reports for expert review.
The CovED platform, which can be accessed anywhere with an internet connection, is being provided for free by the award-winning startup and supported by healthcare experts and leading corporations globally. Medical radiation scientist, educator and CEO Professor Patrick Brennan, of the University of Sydney School of Health Sciences, Faculty of Medicine and Health, said early and better diagnosis would help relieve overburdened healthcare systems and save lives.
“The number of patients that are suffering from this life-threatening illness is fast outpacing the number of skilled staff required to accurately diagnose the required lung CT scans,” Professor Brennan said.
“Our platform does not replace expert medical and radiologic training but CovED provides an effective way to recognise rapidly the appearances of COVID-19, which could be critical in a situation of too many patients and not enough expert radiologists, with the modules taking just 1-2 hours to complete.
“This will be immediately crucial in developing countries, where numbers of radiologists are often insufficient – our tests will help people not only diagnose COVID-19 but also identify potentially life-threatening cases wherever they are.”
DetectED-X’s CovED follows on from the highly successful BreastScreen Reader Assessment Strategy (BREAST) platform, created in 2010 at the University of Sydney, which has been used internationally including in the United States and Europe. Last year the DetectED-X team was commissioned by the Australian government to deliver a similar solution for diagnosing dust disease with high resolution computed tomography (HRCT).
DetectED-X’s approach, which includes algorithms to improve radiologist skills and identifying where errors were made on images in the online training sessions, has been shown to improve results significantly. The CovED platform uses CT images from cases with appearances of COVID-19 arising from Australia (Queensland, Victoria, NSW) and collaborators in Europe.Through CovED, individual clinicians can assess their performance on images on screen, and receive immediate feedback including performance scores used in the industry. The image files personalised for each clinician are instantly returned showing any errors in their virtual diagnosis and the difficulty level is increased over time.
“The World Health Organisation called for solidarity in the global response to COVID-19; DetectED-X answered that call in collaboration with the University of Sydney and industry partners – including GE Healthcare, Volpara, World Continuing Education Alliance (WCEA) and Amazon.
“We are hugely grateful for the support of our industry partners GE Healthcare, Volpara, WCEA and Amazon in making this world-class platform available to help speed up the COVID-19 response,” Professor Brennan said.
University of Sydney Vice-Chancellor and Principal Dr Michael Spence said it was clear from the range of collaborators that global problems attracted global responses. “We are calling on healthcare professionals, and community members alike, to make sure everyone knows this crucial new diagnostic tool to ramp up COVID-19 responses is freely available,” Dr Spence said. Medical professionals, hospitals and other institutions can register to gain access to the platform at www.detectedx.com
CovED is truly an international collaboration of experts in the field including Professor Stuart Grieve from the University of Sydney, respiratory radiologist Dr Sam McCormack from Alfred Imaging Group, Dr Nigel Sommerfeld CEO of Lungscreen Australia, Dr Paul Smith, a consultant radiologist at Epworth, Dr Marcus McMahon, radiologist with Epworth HealthCare, and Professor Greg Fox, respiratory clinician at Royal Prince Alfred Hospital, along with our Italian partners, clinicians at the National Institute for Infectious Diseases in Rome Drs. Fabrizio and Cristofaro.
How it works:
Radiologists will diagnose images using the same drop-down menus and post-processing options that exist clinically.
Each radiologist will give each perceived case a confidence score based on their confidence that a lesion exists. The type of disease appearance is also chosen.
Since truth is known for each case through tissue diagnosis or consensus by DetectED-X expert radiologists, all readings are instantly analyzed using truth algorithms.
Each radiologist will then be able to review the images just read and examine truth alongside correct and incorrect decisions made for each image. The radiologist will be presented with feedback that has been determined by a panel of expert radiologists.
Each radiologist will be given a certificate to recognise completion of the activity with an outline of CME/CPD credits earned. There are a range of point earning options with the ability to complete anything from 1 credit earning module through to 6 credits at a time.
Scores are stored anonymously so that a local or national evaluation of performances can be made which allows reference standards to be defined.