New Discovery Reveals DNA Naturally Fluoresces

A team of researchers at Northwestern University’s Engineering school came across an unprecedented phenomenon: “blinking” or fluorescing DNA.  School textbooks emphasize that macromolecules like DNA and RNA do not naturally fluoresce, and therefore require special fluorescent dyes to be viewed and imaged. This new breakthrough may potentially enable researchers to forgo these often toxic dyes and harness the newly discovered natural fluorescent processes to image DNA.   The toxicity of dy...
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2015 Nobel Prize In Chemistry awarded for mapping how cells repair damaged DNA.

The Nobel Prize in Chemistry 2015 has been awarded to Tomas Lindahl, Paul Modrich and Aziz Sancar “for mechanistic studies of DNA repair.” The three scientists outlined chemical pathways that cells in living things, including human beings, use to repair damaged DNA. "Their work has provided fundamental knowledge of how a living cell functions and is, for instance, used for the development of new cancer treatments," the academy said. The organization tweeted graphics explaining the scientists'...
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Supercoiled DNA is far more dynamic than the “Watson-Crick” double helix

Researchers have imaged in unprecedented detail the three-dimensional structure of supercoiled DNA, revealing that its shape is much more dynamic than the well-known double helix. As reported online today in the journal Nature Communications, the simulations also show the dynamic nature of DNA, which constantly wiggles and morphs into different shapes, a far cry from the commonly held idea of a rigid and static double helix. Improving our understanding of what DNA looks like when it is in the...
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