In early studies on mice, a research team has found a Zika virus antibody that when given to pregnant animals protected their fetuses, and also protected adult mice from the disease. The findings raise hope for a potential treatment to prevent maternal-fetal transmission of the virus to prevent microcephaly and other devastating birth defects until a vaccine is available and also may help guide vaccine development. The team, based at Washington University School of Medicine and Vanderbilt Uni...

Lancaster (UK) based Cardiocity Limited have developed their second variant of the RhythmPad product range to successfully screen from Hypertension through simple hand placement. The RhythmPadGP is a simple USB connected lead1 and 6 lead screening tool. In under 30 seconds the subject’s lead1 and 6 lead ECG may be obtained and analysed giving instant outputs ranging from Sinus Rhythm to Atrial Fibrillation through to Right Bundle Branch Block. The RhythmPadGP makes screening for cardia...

Arterys, a pioneer in cloud-based medical imaging software, announced that it has received 510(k) clearance from the U.S. Food and Drug Administration (FDA) for its Arterys Software. This clearance allows the Arterys product to be used in clinical settings for the quantification of cardiac flow, which includes 4D flow and 2D Phase Contrast workflows, and cardiac function measurements. The product seamlessly integrates into clinical practice to provide comprehensive, simple and quick Cardiac MR i...

TransEnterix Completes Successful Pre-Clinical Robotic Surgical Procedures; Management Affirms FDA Timeline A medical device company that is pioneering the use of robotics and flexible instruments to improve minimally invasive surgery, today announced the successful completion of four general surgery and urology procedures using its SurgiBot system patient-side robotic surgery system. Management also stated that the preparation of its FDA 510(k) filing is proceeding as planned, and affi...

Sunshine matters. A lot. The idea isn't exactly new, but according to a recent BYU study, when it comes to your mental and emotional health, the amount of time between sunrise and sunset is the weather variable that matters most. Your day might be filled with irritatingly hot temperatures, thick air pollution and maybe even pockets of rainclouds, but that won't necessarily get you down. If you're able to soak up enough sun, your level of emotional distress should remain stable. Take away sun ...

Mistakes happen. This is the case in the process of transporting genetic information in cells. How our cells keep errors in this process in check is the subject of a new paper by researchers at the Department of Energy’s Lawrence Berkeley National Laboratory (Berkeley Lab). They found that RNA-binding proteins are regulated such that gateway proteins can recognize and block aberrant strands of genetic code from exiting the nucleus. Unused messenger RNA (mRNA) strands that cannot exit the ...

A team of engineers at the University of California San Diego has developed a magnetic ink that can be used to make self-healing batteries, electrochemical sensors and wearable, textile-based electrical circuits. The key ingredient for the ink is microparticles oriented in a certain configuration by a magnetic field. Because of the way they’re oriented, particles on both sides of a tear are magnetically attracted to one another, causing a device printed with the ink to heal itself. The device...

Affecting 33.5 million patients worldwide, atrial fibrillation is the most common form of cardiac arrhythmia. As if having an irregular heart beat wasn’t troubling enough, patients with atrial fibrillation are also much more likely to have a stroke. Michael Markl “Atrial fibrillation is thought to be responsible for 20 to 30 percent of all strokes in the United States,” said Northwestern’s Michael Markl, the Lester B. and Frances T. Knight Professor of Cardiac Imaging. “While atrial fibril...

Research led by the University shows that stimulation of the brain impacts on endurance exercise performance by decreasing perception of effort. Researchers led by Dr Lex Mauger from Kent’s School of Sport and Exercise Sciences found that tDCS delayed exhaustion of the leg muscles by an average of 15% during an exercise task, and that this was likely caused by the participants feeling less effort during the exercise. However, tDCS elicited no significant effect on the neuromuscular response t...

Newly discovered archaebacteria converts methane into carbon dioxide with the help of iron A microbe that ‘eats’ both methane and iron: microbiologists have long suspected its existence, but were not able to find it - until now. Researchers at Radboud University and the Max Planck Institute for Marine Microbiology in Bremen discovered a microorganism that couples the reduction of iron to methane oxidation, and could thus be relevant in controlling greenhouse gas emissions worldwide. ...

Genetic variants might also impact nicotine and other drug metabolism Depending on a person’s genetic make-up, he or she might be able to guzzle coffee right before bed or feel wired after just one cup, based on continuing research at Northwestern Medicine. Studying how genes impact coffee consumption habits is nothing new. In previous work from Marilyn Cornelis, assistant professor in the department of Preventive Medicine at Northwestern University Feinberg School of Medicine, she identif...

In a proof-of-concept study with mice, scientists at The Johns Hopkins University show that a novel coating they made with antibiotic-releasing nanofibers has the potential to better prevent at least some serious bacterial infections related to total joint replacement surgery. A report on the study, published online the week of Oct. 24 in Proceedings of the National Academy of Sciences, was conducted on the rodents’ knee joints, but, the researchers say, the technology would have “broad appli...

St. Jude Medical's Amplatzer PFO Occluder for patent foramen ovale (PFO) has received FDA approval, the company announced on October 28. The device, made of two nitinol mesh disks with thin polyester fabric, can now be used in the United States to close the PFO—a congenital hole in the tissue between the heart's left and right atria—in patients who have suffered an ischemic stroke, in order to reduce risk of recurrent stroke. Although PFO is relatively common, observed in about a quarter of a...

Nucleotide database is a collection of sequences from several sources, including GenBank, RefSeq, TPA and PDB. Genome, gene and transcript sequence data provide the foundation for biomedical research and discovery. National Library of Medicine / National Institutes of Health. Offers many important databases (PubMed, GenBank, OMIM) and some tools. GenBank sequence database is an open access, annotated collection of all publicly available nucleotide sequences and their protein translations. ...

Thromboelastography (TEG) is a method of testing the efficiency of blood coagulation. It is a test mainly used in surgery and anesthesiology. Thromboelastography is a viscoelastic hemostatic assay that measures the global visco-elastic properties of whole blood clot formation under low shear stress. it shows the interaction of platelets with the coagulation cascade (aggregation, clot strengthening, fibrin cross linking and fibrinolysis). https://youtu.be/SjH05uGSGv0 EG® measures the ph...

The hygiene hypothesis proposes that a 20th century surge in allergies and asthma is because people are living in increasingly hygienic environments. Rather than the rural farm life of the agricultural 19th century, families live in urban and suburban communities, have fewer children who can exchange infections, bathe and wash their hands more frequently, and use antibiotics excessively. This all means reduced infant exposure to microbes that would have tempered excessive immune reactions, such ...

U.S. Food and Drug Administration approved pembrolizumab (KEYTRUDA, Merck & Co., Inc.) for the treatment of patients with metastatic non-small cell lung cancer (NSCLC) whose tumors express PD-L1 as determined by an FDA-approved test. This is the first FDA approval of a checkpoint inhibitor for first-line treatment of lung cancer. This approval also expands the indication in second-line treatment of lung cancer to include all patients with PD-L1-expressing NSCLC. The FDA approval ad...

Kidney cancer—also called renal cell cancer—is one of the major types of cancer for which new immune-based cancer treatments are currently in development. This page features information on kidney cancer and immunotherapy clinical trials for kidney cancer patients, and highlights the Cancer Research Institute’s role in working to bring effective immune-based cancer treatments to kidney cancer patients. In its early stages, kidney cancer typically has no symptoms. As a tumor grows, symptoms may...

Colorado Therapeutics LLC, a privately held medical device company with a proprietary technology platform for the production of innovative cross-linked tissue products, announced today that it has received 510(k) clearance from the U.S. Food and Drug Administration (“FDA”) for a novel xenogenic biologic tissue matrix. The Colorado Therapeutics xenograft implant is intended to be used for implantation to reinforce soft tissue where weakness exists and for the surgical repair of damaged or rupt...

Identifying whether a potential drug is having an effect on cancer cells is not always obvious. If enough cells change their morphology, it’s fairly easy to see the change under a microscope. Spotting individual cells that are unique among millions of others is what researchers at Brown University have been working on. They developed a high speed vision system that outlines cells that just went through an epithelial–mesenchymal transition (EMT). Within tumors such cells lead to greater malignanc...

As humans, we sniff out different scents and aromas using chemical receptors in our noses. In technological gas detection, however, there are a whole host of other methods available. One such method is to use infrared lasers, passing a laser beam through the gas to an adjacent separate detector, which measures the degree of light attenuation it causes. TU Wien's tiny new sensor now brings together both sides within a single component, making it possible to use the same microscopic structure for ...

One may not think that the humble toothbrush is a particularly glamorous health device, but if you scour the Dentistry category here on Medgadget, you’ll quickly discover how important oral health is to your overall health. So important is dental health that October in America has been designated National Dental Hygiene Month. To help commemorate this important month, we were given two electric toothbrushes that have evolved into the “smart” category. These smart toothbrushes feature Bluetooth t...

Recent research suggests that nanotechnologies may lead to the development of novel cancer treatment. Gold nanoparticles with their unique physical and chemical properties hold great hopes for the development of thermal-based therapies against human malignancies. This review will focus on various strategies that have been developed to use gold nanoparticles as photothermal agents against human cancers. Pancreatic cancer begins in the tissues of your pancreas — an organ in your abdomen that li...

Did you know that your brain processes information in a hierarchy? As you are reading this page, the signal coming in through your eyes enters your brain through the thalamus, which organizes it. That information then goes on to the primary visual cortex at the back of the brain, where populations of neurons respond to very specific basic properties. For instance, one set of neurons might fire up because the text on your screen is black and another set might activate because there are vertical l...

This technology is a device that uses electrical activity to facilitate the wound healing process while protecting the wound. The bandage is made of an electroactive material (pictured above) that is stimulated by the heat of the body and the pressure of cell growth, thus no external power source is required. NASA has developed a high-tech electroactive bandage that creates an electric charge to help promote the healing process of wounds. Electroactive material is so sensitive that a push ...

Millions of people worldwide need glasses or contact lenses to see or read properly. We introduce a computational display technology that predistorts the presented content for an observer, so that the target image is perceived without the need for eyewear. By designing optics in concert with prefiltering algorithms, the proposed display architecture achieves significantly higher resolution and contrast than prior approaches to vision-correcting image display. We demonstrate that inexpensive ligh...

Most people notice that they naturally experience different levels of sleepiness and alertness throughout the day, but what causes these patterns? Sleep is regulated by two body systems: sleep/wake homeostasis and the circadian biological clock . When we have been awake for a long period of time, sleep/wake homeostasis tells us that a need for sleep is accumulating and that it is time to sleep. It also helps us maintain enough sleep throughout the night to make up for the hours of being awake...

Astronauts know their bodies will be tested during time spent on the International Space Station, from the 15 daily sunrises and sunsets wreaking havoc on their circadian rhythms to the lack of gravity that weakens bone density and muscle. NASA is working to counteract these otherworldly challenges to enable long-term human exploration of space. For example, special lighting helps with sleep, and rigorous exercise helps keep astronauts’ bodies strong. But, frustratingly, bone loss continue...

Nanoparticles known as Cornell dots, or C dots, have shown great promise as a therapeutic tool in the detection and treatment of cancer. Now, the ultrasmall particles – developed more than a dozen years ago by Ulrich Wiesner, the Spencer T. Olin Professor of Engineering – have shown they can do something even better: kill cancer cells without attaching a cytotoxic drug. A study led by Michelle Bradbury, director of intraoperative imaging at Memorial Sloan Kettering Cancer Center and associ...