Researchers have discovered that a protein found naturally in cells that provides some protection from viruses is responsible for creating mutations that drive resistance to tamoxifen treatment in breast cancer. Because the protein, known as APOBEC3B, is found in elevated quantities in other kinds of cancer cells, the finding explains differential responses to treatment and opens the door to boosting the effectiveness of tamoxifen and related breast cancer therapies that inhibit the ability of e...

Far too many diseases do not have a proven means of prevention or effective treatments. We must gain better insights into the biological, environmental, and behavioral influences on these diseases to make a difference for the millions of Americans who suffer from them. Precision medicine is an emerging approach for disease treatment and prevention that takes into account individual variability in genes, environment, and lifestyle for each person. While some advances in precision medicine have be...

Photoswitches are a family of small-molecules designed to photo-modulate the activity of specific signaling proteins: One color turns the protein ‘on’; a different color turns it ‘off’. Photoswitches were conceived at the Nanomedicine Development Center for the Optical Control of Biological Function at UC Berkeley Light-sensitive proteins are changing the way scientists study how new drug candidates affect critical properties of heart and nerve cells. The proteins, discovered by Max Planck re...

Poze is the most user-friendly and affordable way to improve your posture. They have cut the noise and focused on a real problem: how to avoid bad habits. Poze is a wearable device that has no app, no charging, and no diagrams. The certified technology calculates the angle of your back’s posture. If you slouch for 1 minute, Poze silently buzzes reminding you to straighten back up. In 3 weeks your muscles will feel normal when sitting or standing tall. Attach Poze with a self-adhesive hypo-all...

Nanoscale secondary ion mass spectrometry (nanoSIMS or nano secondary ion mass spectrometry) is a nanoscopic scale resolution chemical imaging mass spectrometer based on secondary ion mass spectrometry. It works based on a coaxial optical design of the ion gun and the secondary ion extraction, and on an original magnetic sector mass spectrometer with multicollection. NanoSIMS not only refers to the technique used, but also the mass spectrometer specialized for this method. There are currently...

LVL is a hydration monitor from BSX, You might know that name from the company’s first product, the Insight lactate threshold monitor. Why Monitor Hydration? Think of LVL as the evolution of that technology, says BSX co-founder Dustin Freckleton, MD. “Lactate threshold was always a mid-range goal on the way to what we truly wanted to do, which was measure hydration,” he says. Freckleton’s interest is partly personal: in the midst of studying for med school exams, he suffered a stroke partly ...

Northwestern Medicine scientists, working with the Pediatric Emergency Care Applied Research Network (PECARN), recently assessed whether an RNA biosignature of the body’s response to infection could distinguish if infants 60 days or younger with fever were experiencing a serious bacterial infection. The results, published in the Journal of the American Medical Association, show how RNA biosignatures may be an alternative – and more accurate – method to identify infants with bacterial infectio...

Phototactic behaviour directs some bacteria towards light and others into darkness: This enables them to utilize solar energy as efficiently as possible for their metabolism, or, otherwise, protects them from excessive light intensity. A team of researchers headed by Clemens Bechinger from the Max Planck Institute for Intelligent Systems and the University of Stuttgart, as well as colleagues from the University of Düsseldorf have now found a surprisingly simple way to direct synthetic microswimm...

Developing oral care products to prevent and treat oral diseases requires model systems to test the potential therapies before applying them to humans. However, the ability of current models to accurately reflect human oral physiology or predict the effects of therapies on the human disease state is limited, and can be a rate limiting stage of the development process. Colgate-Palmolive is working with Draper to create an advanced gum tissue model that improves the predictive power of the testing...

GE Healthcare’s MAGiC, which stands for magnetic resonance image compilation, has received 510(k) clearance from the FDA. Providing the industry’s first multi-contrast MR technique, the system provides clinicians with more data than conventional scanning in a much shorter period of time. Users can manipulate MR images retrospectively, and that can lead to substantial time-savings, a reduction in rescans, and an increase in cost savings. MAGiC (Magnetic Resonance Image Compilation) is the indu...

MolecuLight i:X uses the principle of fluorescence to capture and document either still images or videos of wounds as well as their surrounding areas where potentially harmful bacteria may be present, without the need of contrast agents. MolecuLight’s first product, the i:X, is a handheld fluorescence imaging device that allows clinicians to quickly, safely, and easily visualize and precisely target bacterial presence and distribution in and around wounds, in real-time at the point-of-care. T...

San Francisco-based digital health startup Augmedix is now trying to establish a mass market for Google Glass in the healthcare industry. Augmedix, which adapted Google Glass to help doctors take notes as they examine patients, is earning revenues from hundreds of physicians who subscribe to the company’s service, CEO Ian Shakil says. Augmedix, founded in 2012 by Shakil, now counts users in almost all U.S. states. Every day, the company says, about 5,000 patients see a doctor who wears a G...

Chemical contrast has long been sought for label-free visualization of biomolecules and materials in complex living systems. Although infrared spectroscopic imaging has come a long way in this direction, it is thus far only applicable to dried tissues because of the strong infrared absorption by water. It also suffers from low spatial resolution due to long wavelengths and lacks optical sectioning capabilities. We overcome these limitations through sensing vibrational absorption–induced photothe...

Sound can now be structured in three dimensions. Researchers from the Max Planck Institute for Intelligent Systems and the University of Stuttgart have found a way of generating acoustic holograms, which could improve ultrasound diagnostics and material testing. The holograms can also be used to move and manipulate particles. Shaped with ultrasound: Max Planck researchers from Stuttgart transmit ultrasonic waves through a bath of water © Kai Melde / MPI for Intelligent Systems Pee...

Northwestern University research team has developed a 3-D printable ink that produces a synthetic bone implant that rapidly induces bone regeneration and growth. This hyperelastic “bone” material, the shape of which can be easily customized, one day could be especially useful for the treatment of bone defects in children. Bone implantation surgery is never an easy process, but it is particularly painful and complicated for children. With both adults and children, often times bone is harvested...

Researchers from the Max Planck Institute for Human Cognitive and Brain Sciences in Leipzig and the University, have identified neural mechanisms that help us understand whether a difficult and complex social situation is emotionally positive or negative. “When someone offends you while smiling, should your brain interpret it as a smile or an offense? The mechanism we found includes two areas in the brain that act almost as ‘remote controls’ that together determine what value to attribute to a s...

Oxytocin has been dubbed the “love hormone” for its role promoting social bonding, altruism and more. Oxytocin occurs naturally in the body. Produced by the hypothalamus, it acts as a hormone and as a neurotransmitter, affecting many regions of the brain. It is stimulated during sex, childbirth, and breastfeeding. Recent research has highlighted oxytocin’s role in promoting empathy, trust, social bonding, and altruism. In a new study from Duke University, men reported a greater sense of...

One in three Americans suffers from chronic pain. 1 Chronic pain is defined as pain lasting more than three months, and it can interfere with your daily activities, impact your mood, and prevent you from sleeping soundly. Quell can provide widespread relief from chronic pain, and may be right for you. Living with chronic pain can be devastating. Even getting out of bed in the morning can be difficult. Pain affects all aspects of your life – your ability to work, to be in relationships with ot...

Porticos engineers combined technical expertise with practical specifications to develop Livi™, the advanced precision medication-dispensing device.  It delivers prescription-specific dosages of multiple  medications for advanced patient home care. Direct-loading by a retail pharmacy will ensure precise, controlled medication dispensing for up to three months. Livi™ dispenses medicines as scheduled. Internet-enabled remote oversight and comprehensive medication-adherence reports improve coord...

Researchers at MIT's Computer Science and Artificial Intelligence Lab (CSAIL) have found a way to detect human emotions purely through radio signals. Using a device called the EQ-Radio, which emits and captures reflected radio frequency (RF) waves, the researchers bounced waves off subjects to measure their breathing patterns and heart rates. As Computer Science and Artificial Intelligence Laboratory (CSAIL) researchers Mingmin Zhao, Fadel Adib and Dina Katabi describe in their paper, "Emotio...

Global Kinetics Corporation with researchers from the Florey Neuroscience Institute, presents the Personal KinetiGraph™ (PKG™) movement recording. The PKG™ Data Logger is a wrist worn device, that looks like a wristwatch, that automatically records movement data to assist Doctors in their diagnosis and treatment of the symptoms of movement disorders. The PKG™ Data Logger is worn like a wrist watch and features a vibrating reminder of when patients should register that they have taken their le...

Eko Core is a complete electronic stethoscope with digital & analog capabilities that wirelessly pairs to the free Eko Mobile App for recording, visualization. Eko Core digital electronic stethoscope connects to a smartphone. Amplify, visualize & record heart & lung sounds. Visualize, record, and share sounds wirelessly from Eko Core to your Apple or Android mobile device in real time with the app. Live stream stethoscope sounds from the Eko Core to other clinicians anyw...

For those who suffer from impaired walking, a sedentary lifestyle in a wheelchair seems like the only viable option. The makers of UPnRIDE however, have create a solution that changes the way we think about mobility for the disabled. UPnRIDE, a wheeled robotic device, enables both upright and seated mobility for anyone who is unable to, or has difficulty standing or walking. Millions of people who suffer from impaired walking use wheelchairs which limit their mobility, leading to health decli...

University of Washington computer scientists and electrical engineers have come together to develop HemaApp: an application that uses a smartphone camera to estimate hemoglobin concentrations. Anemia, a blood condition exacerbated by malnutrition or parasitic disease, is a common health problem in the developing world that is often undiagnosed. Currently, in order to detect hemoglobin levels, most health care providers either use an invasive technique (i.e. a needle) or expensive machines tha...

University of Washington scientists have developed a way to link your smartphones to your contact lenses using a new technology called the "interscatter communication.” Using this technology, medical aid such as contact lenses and brain implants can send signals to smartphones. The "interscatter communication" works by converting Bluetooth signals into Wi-Fi signals. (Elaborate more here on the technology.) This technology will create Wi-Fi by using Bluetooth transmissions from nearby mobi...

Augmentative and alternative communication (AAC) is an umbrella term that encompasses the communication methods used to supplement or replace speech or writing for those with impairments in the production or comprehension of spoken or written language. AAC is used by those with a wide range of speech and language impairments, including congenital impairments such as cerebral palsy, intellectual impairment and autism, and acquired conditions such as amyotrophic lateral sclerosis and Parkinson's d...

A research team, led by an IU School of Health and Rehabilitation faculty member at Indiana University-Purdue University Indianapolis, has determined that adapted yoga is both feasible and beneficial for adults with stroke or traumatic brain injury. Subjects in a recently published study of adults with traumatic brain injury demonstrated improved balance, flexibility, strength, endurance and walking speed after participation in adapted yoga. The study underscores the belief that adapted yoga m...

Our brains have a detailed picture of our hands and fingers, and that persists even decades after an amputation, Oxford University researchers have found. The finding could have implications for the control of next generation prosthetics. Team leader, Dr. Tamar Makin said: 'It has been thought that the hand 'picture' in the brain, located in the primary somatosensory cortex, could only be maintained by regular sensory input from the hand. In fact, textbooks teach that the 'picture' ...

Early experiences affect the development of brain architecture, which provides the foundation for all future learning, behavior, and health. Just as a weak foundation compromises the quality and strength of a house, adverse experiences early in life can impair brain architecture, with negative effects lasting into adulthood. The development of a child’s brain architecture provides the foundation for all future learning, behavior, and health.Brains are built over time, from t...

Encounters with nearby nature help alleviate mental fatigue by relaxing and restoring the mind. Within built environments parks and green spaces are settings for cognitive respite, as they encourage social interaction and de-stressing through exercise or conversation, and provide calming settings. Having quality landscaping and vegetation in and around the places where people work and study is a good investment. Both visual access and being within green space helps to restore the mind’s ability ...