UNIVERSITY OF EDINBURGH London research found small genetic contributions to self-reported tiredness and low energy

Already feeling drained so early in the year? Genes might contribute in a small but significant way to whether people report being tired and low in energy. This is according to UK researchers led by Vincent Deary of Northumbria University, Newcastle, and Saskia Hagenaars of the University of Edinburgh, in a paper in Springer Nature’s journal Molecular Psychiatry. They found that genetics accounts for about eight percent of people’s differences in self-reported tiredness/low energy; this impli...
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A study led by Queen Mary University of London (QMUL) finds that vitamin D supplements protect against acute respiratory infections including colds and flu

  If you've repeatedly fallen for this annual propaganda campaign, you may be surprised to find the medical literature suggests vitamin D may actually be a FAR more effective strategy, and the evidence for this goes back at least a decade. Dr. John Cannell, founder of the Vitamin D Council, was one of the first to introduce the idea that vitamin D deficiency may actually be an underlying CAUSE of influenza. Vitamin D protects against colds and flu, finds major global study Overall, ...
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Waseda University Japan, researchers have developed new cheaper way of producing electronic devices that are flexible, elastic, and adhere to the skin.

Waseda University researchers have developed processes and materials for ultrathin stick-on electronic devices using elastomeric “nanosheet” film, achieving ease of production while also preserving high elasticity and flexibility fifty times better than previously reported polymer nanosheets. Black lines are simply printed on the nanosheet, but are able to conduct electricity   This research is published in the Journal of Materials Chemistry C online edition, February 1, 2017. ...
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Ulsan National Institute of Science and Technology South Korea has created a metal-based substance that works to cut out amyloid-β, the protein vital for the development of Alzheimer’s disease

Ulsan National Institute of Science and Technology, or UNIST, in South Korea has created a metal-based substance that works to cut out amyloid-β, the protein vital for the development of Alzheimer's disease. Researchers found that by hydrolyzing, a process of splitting a molecule apart using water, amyloid-beta proteins using a crystal structure called tetra-N methylated cyclam, or TMC, they could reduce the toxicity of Aβ. The team used cobalt, nickel, copper and zinc placed at the center...
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Researchers At Seoul National University have developed ‘smart contact lenses’ that are capable of protecting eyes from electromagnectic (EM) waves that may cause eye diseases such as cataracts.

Recently, smart contact lenses with electronic circuits have been proposed for various sensor and display applications where the use of flexible and biologically stable electrode materials is essential. Graphene is an atomically thin carbon material with a two-dimensional hexagonal lattice that shows outstanding electrical and mechanical properties as well as excellent biocompatibility. In addition, graphene is capable of protecting eyes from electromagnectic (EM) waves that may cause eye dis...
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Duke University researchers have discovered a way to detect signs of cancer on a cell-by-cell basis using two lasers and a camera

Biomedical engineers at Duke University have discovered a way to detect signs of cancer on a cell-by-cell basis using two lasers and a camera. Several medical devices currently in use and in clinical trials around the world look for increases in cellular stiffness as an indicator of cancerous tissue. These devices, however, rely on readings from many cells clustered together within the body and cannot operate on a cellular level. In a study published online Feb. 28 in the Biophysical Journ...
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Neocis Inc’s ‘Yomi’ is the first robotic dental surgery system approved by FDA

Yomi is a computerized navigational system intended to provide assistance in both the planning (pre-operative) and the surgical (intra-operative) phases of dental implantation surgery. The system provides software to preoperatively plan dental implantation procedures and provides navigational guidance of the surgical instruments. “I’ve done thousands of implants free-hand. Yomi will be a game changer for dental implant surgery.” https://youtu.be/l2L2I5rtLcY Dental implant surgery is the sta...
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Muscular Dystrophy Association research update on ‘muscular atrophy’

Muscle atrophy is defined as a decrease in the mass of the muscle; it can be a partial or complete wasting away of muscle, and is most commonly experienced when persons suffer temporary disabling circumstances such as being restricted in movement and/or confined to bed as when hospitalized. When a muscle atrophies, this leads to muscle weakness, since the ability to exert force is related to mass. Modern medicine's understanding of the quick onset of muscle atrophy is a major factor behind the p...
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Stanford University researchers have developed a brain-to-computer hookup that can enable people with paralysis to type via direct brain control at the highest speeds and accuracy levels reported to date.

A clinical research paper led by Stanford University investigators has demonstrated that a brain-to-computer hookup can enable people with paralysis to type via direct brain control at the highest speeds and accuracy levels reported to date. The report involved three study participants with severe limb weakness — two from amyotrophic lateral sclerosis, also called Lou Gehrig’s disease, and one from a spinal cord injury. They each had one or two baby-aspirin-sized electrode arrays placed...
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University College London research suggest long-term stress can result in higher levels of obesity

People who suffer long-term stress may also be more prone to obesity, according to research by scientists at UCL which involved examining hair samples for levels of cortisol, a hormone which regulates the body’s response to stress. The paper, published in the journal Obesity, showed that exposure to higher levels of cortisol over several months is associated with people being more heavily, and more persistently, overweight. The prevalence of overweight and obesity has markedly increased duri...
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FDA approves Vidas Brahm’s ‘PCT Assay’ to help determine if antibiotic treatment should be started or stopped

The U.S. Food and Drug Administration has cleared the expanded use of the Vidas Brahms PCT Assay to help health care providers determine if antibiotic treatment should be started or stopped in patients with lower respiratory tract infections, such as community-acquired pneumonia, and stopped in patients with sepsis. This is the first test to use procalcitonin (PCT), a protein associated with the body’s response to a bacterial infection, as a biomarker to help make antibiotic management decisions...
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University of Melbourne research on effectiveness of online exercise sessions by a physiotherapist to treat chronic knee osteoarthritis

University of Melbourne research has found that treating chronic knee osteoarthritis  by conducting online exercise sessions by a physiotherapist (via Skype), combined with an automated online pain-coping program, has substantial benefits for improving pain, function and quality of life. Treating chronic knee osteoarthritis is set to go “virtual” after new research found that exercise delivered by a physiotherapist via Skype, combined with an automated online pain-coping program, has substant...
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NASA’s Space Food Bars That Will Keep Orion Weight Off and Crew Weight On

When astronauts in the Orion spacecraft travel beyond the moon to explore deep space destinations, they’ll need a robust diet to keep them healthy and sharp. While crew members aboard the International Space Station can choose from approximately 200 items for their meals and have the space to stow an array of options, feeding the crew on deep space missions presents several unique challenges that NASA scientists are working to tackle. Orion has limited room inside it to accommodate the suppli...
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Medicinal plants

Healing with medicinal plants is as old as mankind itself. The connection between man and his search for drugs in nature dates from the far past, of which there is ample evidence from various sources: written documents, preserved monuments, and even original plant medicines. Awareness of medicinal plants usage is a result of the many years of struggles against illnesses due to which man learned to pursue drugs in barks, seeds, fruit bodies, and other parts of the plants. Contemporary science ...
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‘Sonoporation’ Gene transfer using ultrasound

Sonoporation, or cellular sonication, is the use of sound (typically ultrasonic frequencies) for modifying the permeability of the cell plasma membrane. This technique is usually used in molecular biology and non-viral gene therapy in order to allow uptake of large molecules such as DNA into the cell, in a cell disruption process called transfection or transformation. Sonoporation employs the acoustic cavitation of microbubbles to enhance delivery of these large molecules. The bioactivity of ...
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University Of South California research suggest fasting triggers stem cell regeneration of damaged, old immune system

In the first evidence of a natural intervention triggering stem cell-based regeneration of an organ or system, a study in the June 5 issue of the Cell Stem Cell shows that cycles of prolonged fasting not only protect against immune system damage — a major side effect of chemotherapy — but also induce immune system regeneration, shifting stem cells from a dormant state to a state of self-renewal. In both mice and a Phase 1 human clinical trial involving patients receiving chemotherapy, long pe...
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University of Tokyo suggest calcium controls sleep duration. Change in calcium concentration in neurons determines sleep or waking state

University of Tokyo and RIKEN researchers have identified seven genes responsible for causing mice to stay awake or fall asleep based on a theoretical model of sleep and on experiments using 21 different genetically-modified mice, some of which showed different sleep durations. Researchers hope that their research will contribute to the understanding and treatment of sleep disorders and associated neurodegenerative diseases. All animals appear to sleep for varying durations. In humans, sleep ...
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Carnegie Mellon University study provides the first biological evidence that suggest that married people are healthier than those who are single, divorced or widowed.

Studies have suggested that married people are healthier than those who are single, divorced or widowed. A new Carnegie Mellon University study provides the first biological evidence to support that claim. Published in Psychoneuroendocrinology, the researchers found that married individuals had lower levels of the stress hormone cortisol than those who never married or were previously married. These findings support the belief that unmarried people face more psychological stress than married in...
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Nova Southeastern University (NSU) research suggest immune genes, legumain and Bag1 in sharks have unique rapid healing power and high resistance to cancer

New genomics study of shark DNA, including from great white and great hammerhead sharks, reveals unique modifications in their immunity genes that may underlie the rapid wound healing and possibly higher resistance to cancers in these ocean predators.  This research brings us a few steps closer to understanding, from a genetic sense, why sharks exhibit some characteristics that are highly desirable by humans. Sharks and rays are well known to be highly efficient wound healers, and suspected ...
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Engineers and biologists at MIT have developed Living sensors bandages that light up when in contact with certain chemicals

Engineers and biologists at MIT have teamed up to design a new “living material” — a tough, stretchy, biocompatible sheet of hydrogel injected with live cells that are genetically programmed to light up in the presence of certain chemicals. In a paper published this week in the Proceedings of the National Academy of Sciences, the researchers demonstrate the new material’s potential for sensing chemicals, both in the environment and in the human body. The team fabricated various wearable sensor...
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University of Sussex research suggest, child obesity inherited from parents (35-40%)

Around 35-40 per cent of a child’s BMI – how fat or thin they are – is inherited from their parents, a new study has found. For the most obese children, the proportion rises to 55-60 per cent, suggesting that more than half of their tendency towards obesity is determined by genetics and family environment. The study, led by the University of Sussex, used data on the heights and weights of 100,000 children and their parents spanning six countries worldwide: the UK, USA, China, Indonesia, Sp...
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University of Leicester (UK) research suggest, neurodegeneration that occurs in Parkinson’s disease is a result of stress on the endoplasmic reticulum in the cell rather than failure of the mitochondria as previously thought

The neurodegeneration that occurs in Parkinson’s disease is a result of stress on the endoplasmic reticulum in the cell rather than failure of the mitochondria as previously thought, according to a study in fruit flies. It was found that the death of neurons associated with the disease was prevented when chemicals that block the effects of endoplasmic reticulum stress were used. Some inherited forms of early-onset Parkinson’s disease have typically been blamed on poorly functioning mitochondr...
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Researchers at the University of Tokyo suggest, maternal mRNAs act as templates to produce numerous proteins that support biological activities immediately after fertilization

Researchers at the University of Tokyo have demonstrated that “codons,” the units of the genetic code that specifies the sequence of amino acids in proteins, also determine the stability of maternally derived messenger RNA (mRNA) in fertilized eggs. This discovery has revealed a previously unknown function of the genetic code and its importance in animal development. In animals, mRNAs derived from the maternal genome (maternal mRNAs) are stored in fertilized eggs and act as templates to produ...
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National Institute Of Health Study on Optogenetics – biological technique which involves the use of light to control cells can also control brain

Optogenetics is a biological technique which involves the use of light to control cells in living tissue, typically neurons, that have been genetically modified to express light-sensitive ion channels. It is a neuromodulation method employed in neuroscience that uses a combination of techniques from optics and genetics to control and monitor the activities of individual neurons in living tissue—even within It is a neuromodulation method employed in neuroscience that uses a combination of tech...
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‘ Na-Nose’- A Nanoscale Artificial Nose to Detect Specific Medical Conditions

Respiratory infections are a leading cause of mortality and morbidity worldwide. Respiratory pathogenic bacteria, such as Streptococcus pneumoniae and Haemophilus influenza, are the main causes for chronic respiratory conditions, such as Chronic Obstructive Pulmonary Disease (COPD). Advanced stages of these conditions lead to poor quality of life, limited flexibility in practicing daily physical activity, and an increased risk of death. Altogether, these disease conditions lead to considerable h...
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UCLA neuroscience research suggests, people who had the strongest responses in the areas of the brain associated with perceiving pain and emotion and imitating others were also the most generous.

Your brain might be hard-wired for altruism It’s an age-old quandary: Are we born “noble savages” whose best intentions are corrupted by civilization, as the 18th century Swiss philosopher Jean-Jacques Rousseau contended? Or are we fundamentally selfish brutes who need civilization to rein in our base impulses, as the 17th century English philosopher Thomas Hobbes argued? After exploring the areas of the brain that fuel our empathetic impulses — and temporarily disabling other regions that o...
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University Of Melbourne research team has developed method to accurately identify a term baby who is at risk of stillbirth

We don’t know the full causes of stillbirth, but in about half of cases it is caused by the placenta not working properly. The placenta feeds and oxygenates the baby so when it isn’t working well babies become growth restricted. Fetuses that are growth restricted are at 3-4 times increased risk of stillbirth. So, finding a test that accurately flags babies that are growth restricted and intervening early may be the key to reducing stillbirths. But it is surprisingly hard to identify such grow...
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University of Tokyo research on ALS suggest, damage caused by the protein-cutting enzyme calpain to the critical pathway shuttling essential molecules between the cell’s nucleus and cytoplasm leads to the death of nerve cells.

University of Tokyo research group and their collaborators have shed light on one of the mechanisms responsible for the onset of sporadic ALS—a non-genetic form of the neurodegenerative disorder also known as Lou Gehrig’s disease—by demonstrating in an experiment with mice that damage caused by the protein-cutting enzyme calpain to the critical pathway shuttling essential molecules between the cell’s nucleus and cytoplasm leads to the death of nerve cells. The current outcome holds promise of ad...
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National Institute Of Health research suggest, diet can affect certain autoimmune diseases via gut microbes

In autoinflammatory diseases, the innate immune system, for unknown reasons, becomes activated and triggers inflammation. This part of the immune system is the body’s rapid first line of defense against infection. The short-term heat, swelling, and redness of inflammation are a normal part of the body’s protective response to injury or infection. But prolonged inflammation can seriously damage the body. Recent research suggests that diet can affect certain autoimmune diseases. A team led by D...
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Engineers at MIT have fabricated transparent, hydrogel – gel-based robots that may one day assist in surgical operations

Engineers at MIT have fabricated transparent, gel-based robots that move when water is pumped in and out of them. The bots can perform a number of fast, forceful tasks, including kicking a ball underwater, and grabbing and releasing a live fish. The robots are made entirely of hydrogel — a tough, rubbery, nearly transparent material that’s composed mostly of water. Each robot is an assemblage of hollow, precisely designed hydrogel structures, connected to rubbery tubes. When the researchers p...
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